Abstract & Thesis Samples
APPENDIX B (Sample Abstract)
ABSTRACT
LEPTIN ACTIVATES ENTERIC NEURONS IN THE RAT SMALL INTESTINE
By
Shani Titania Lampley
Leptin is the protein product of the ob gene in white adipose tissue. Leptin is a hormone involved in the regulation of energy balance and food intake through activation of neuronal populations in the arcuate and paraventricular nuclei of the hypothalamus. These nuclei communicate with some satiety centers in the hindbrain, namely the area postrema (AP), nucleus of the solitary tract (NTS) and dorsal motor nucleus of the vagus (DMV). The NTS and DMV connect with the nervous system of the gastrointestinal tract (GI tract), also known as enteric nervous system (ENS), through the vagus nerve. The ENS consists of two main plexuses: myenteric plexus and submucosal plexus, and is responsible for most of the functions in the GI tract e.g., secretion and motility.
Here we investigated activation of AP, NTS, and DMV as well as ENS neurons in the duodenum, jejunum, and ileum of adult, male Sprague-Dawley rats injected with 0.25, 0.5, and 10 mg/kg leptin or vehicle (15 mM HCL and 7.5 mM NaOH, pH 5.2) utilizing the detection of Fos-immunoreactivity in these neurons. Fos is the protein product of the immediate early gene c-fos, which has been used extensively as a marker for neuronal activation.
We confirmed a previously reported finding that intraperitoneal injection of leptin increased Fos-immunoreactivity in the AP, NTS, and the DMV. Also, we found that 0.5 mg/kg leptin increased c-fos expression in the enteric neurons of the duodenum, jejunum and ileum. Thus, we conclude that the ENS and the hindbrain may have a role in activation by leptin.
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APPENDIX C (SAMPLE TITLE PAGE)
LEPTIN ACTIVATES ENTERIC NEURONS IN THE RAT SMALL
INTESTINE
By
Shani Titania Lampley
A Thesis Submitted to the Graduate Faculty
of Tuskegee University
in Partial Fulfillment of the Requirements
of the Degree
MASTER OF SCIENCE IN BIOLOGY
TUSKEGEE UNIVERSITY
Tuskegee, Alabama 36088
May 2008
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APPENDIX D (SAMPLE THESIS – DISSERTATION APPROVAL PAGE
THESIS/DISSERTATION APPROVED BY:
___________________________
Major Professor
_________________________
Dean of College
__________________________________
Dean of Graduate Programs
FOR:
___________________________
Student
_______________________________
Title of Thesis
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APPENDIX E (SAMPLE TITLE PAGE FOR DOCTORAL DISSERTATION)
Dissertation Title
by
Student's Name
A Dissertation Submitted to the Graduate Faculty of Tuskegee University
in Partial Fulfillment of the Requirements for the Degree of
DOCTOR OF PHILOSOPHY IN MATERIALS SCIENCE AND
ENGINEERING
TUSKEGEE UNIVERSITY
Tuskegee, Alabama 36088
May 2008
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DISSERTATION APPROVED BY
_____________________________
Major Professor
_________________________________
Committee Member
_________________________________
Committee Member
_________________________________
Committee Member
_________________________________
Committee Member
__________________________ ______________________________
Director, PhD Program (MSE) Dean, College of Engineering,
Architecture and Physical Sciences
_______________________________________
Dean of Graduate Programs
For
Student's Name
Title of Dissertation
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